T-cell rosettes in nodular lymphocyte–predominant Hodgkin lymphoma

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Nodular Lymphocyte Predominant Hodgkin Lymphoma With Nodules Resembling T-Cell/Histiocyte Rich B-Cell Lymphoma Differential diagnosis between nodular lymphocyte predominant Hodgkin lymphoma and T-cell/ histiocyte rich B-cell lymphoma Short title: nodular lymphocyte predominant Hodgkin lymphoma

Ludmila Boudová, M. D., Emina Torlakovic, M. D., Jan Delabie, M.D., Peter Reimer, M.D., Beate Pfistner, Ph. D., Sabine Wiedenmann, M. D., Volker Diehl, M.D., Hans-Konrad Müller-Hermelink, M. D., Thomas Rüdiger, M. D. Department of Pathology, Charles University, Pilsen, Czech Republic, Department of Pathology, The Norwegian Radium Hospital, Oslo, Norway, 3 Medizinische Poliklinik, University of ...

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Nodular lymphocyte-predominant Hodgkin lymphoma with nodules resembling T-cell/histiocyte-rich B-cell lymphoma: differential diagnosis between nodular lymphocyte-predominant Hodgkin lymphoma and T-cell/histiocyte-rich B-cell lymphoma.

Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) and T-cell/histiocyte-rich B-cell lymphoma (T/HRBCL) are distinct tumors and are treated differently. They are linked by a morphologic and probably a biologic continuum, which renders the differential diagnosis difficult. To develop criteria to distinguish the entities along the morphologic continuum, we correlated the lymph node architect...

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T-cell non-Hodgkin lymphoma.

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Nodular Lymphocyte Predominant Hodgkin Lymphoma versus T-Cell/Histiocyte-Rich Large B-Cell Lymphoma: A Diagnostic Challenge

Lymphomas with overlapping histological features of two distinct entities cause difficulty in classification. Their classification is of particular significance when the two alternatives require different treatment modalities. We present a diagnostically challenging case of a nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) with features of T-cell/histiocyte-rich large B-cell lymphoma (T...

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Hematopathology / NODULAR LYMPHOCYTE PREDOMINANT HODGKIN LYMPHOMA

In our experience, certain commonly cited immunophenotypic features of nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) are not encountered in day-to-day practice. We reviewed 60 cases of NLPHL (18 women, 42 men; median age, 34 years) to discern immunophenotypic features from a large, single-institution cohort. All cases contained lymphocytic and histiocytic (L&H) cells. These cells expr...

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ژورنال

عنوان ژورنال: Blood

سال: 2017

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood-2016-10-745802